TUESDAY, June 1, 2021 (HealthDay News) – The incidence of cervical cancer has decreased while the incidence of other cancers associated with human papillomavirus (HPV) has increased in the United States, according to a study based on the American Society of Clinical Oncology Annual Meeting, held virtually June 4-8.
Cheng-I Liao, MD, of Kaohsiung Veterans General Hospital in Taiwan, and colleagues obtained data from the U.S. Cancer Statistics program from 2001 to 2017 and examined trends in the incidence of HPV-associated cancers.
The researchers found that the overall incidence of HPV-related cancers in women was 13.68 / 100,000, of which 52 percent were cervical cancer (7.12 / 100,000 in 2017). The incidence of cervical cancer decreased with an annual percentage change (APC) of 1.03 percent, while the incidence rates of oropharyngeal, anal and rectal, and squamous cell carcinoma of the vulva increased (APCs 0.77, 2.75 and 1.27 percent, respectively ). . The incidence of anal and rectal cancer in older women approached that of cervical cancer. By 2025, the incidence of anal and rectal cancer is expected to exceed that of cervical cancer in any age group over 55 years of age. The incidence of all HPV-related cancers in men was 11.0 / 100,000 in 2017; 81 percent were associated with oropharyngeal cancer. From 2001 to 2017, men had an annual increase in HPV-related cancers of 2.36 percent per year.
“Without standardized screening, HPV-related cancers such as oropharyngeal cancer and anal rectal cancer will increase,” Liao said in a statement. “To reduce these trends and achieve results comparable to those seen with cervical cancer, we need to develop effective screening strategies and determine the effectiveness of the vaccine in these patient populations.”
One author announced financial ties to the pharmaceutical industry.